"Sophie Bangs was a just an ordinary college student in a weirdly futuristic New York when a simple assignment changed her life forever: while researching Promethea, a mythical warrior woman, [she] receives a cryptic warning to cease her investigations. Ignoring the cautionary notice, she continues her studies and is almost killed by a shadowy creature when she learns the secret of Promethea. Surviving the encounter, Sophie soon finds herself transformed...

Six adventurers, Allan Quatermain, Captain Nemo, Hawley Griffin, Dr. Henry Jekyll, Mr. Edward Hyde, and Mina Murray, are pressed into service by their empire in it's time of need.